KEAP1/NRF2 Mutations in Stem Cells Define an Aggressive Subset of Head and Neck Cancer Patients Who Have a Poor Prognosis, Lung Metastasis, and Therapeutic Failure

SIMPLE SUMMARY: Mutations in head and neck cancer result in abnormal tumor cell growth, increase the risk of distant metastasis, and lead to therapeutic failure. Progenitor cells, head and neck cancer stem cells, and bulk tumor cells may all harbor these mutations, and identifying the mutations in s...

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Detalles Bibliográficos
Autores principales: Islam, Syed S., Karakas, Bedri, Aboussekhra, Abdelilah, Noman, Abu Shadat M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605399/
https://www.ncbi.nlm.nih.gov/pubmed/37894373
http://dx.doi.org/10.3390/cancers15205006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605399/
https://www.ncbi.nlm.nih.gov/pubmed/37894373
http://dx.doi.org/10.3390/cancers15205006

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