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KEAP1/NRF2 Mutations in Stem Cells Define an Aggressive Subset of Head and Neck Cancer Patients Who Have a Poor Prognosis, Lung Metastasis, and Therapeutic Failure
SIMPLE SUMMARY: Mutations in head and neck cancer result in abnormal tumor cell growth, increase the risk of distant metastasis, and lead to therapeutic failure. Progenitor cells, head and neck cancer stem cells, and bulk tumor cells may all harbor these mutations, and identifying the mutations in s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605399/ https://www.ncbi.nlm.nih.gov/pubmed/37894373 http://dx.doi.org/10.3390/cancers15205006 |