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Opposing Roles for the α Isoform of the Catalytic Subunit of Protein Phosphatase 1 in Inside–Out and Outside–In Integrin Signaling in Murine Platelets
Platelet activation during hemostasis and thrombosis is facilitated by agonist-induced inside–out and integrin α(IIb)β(3)-initiated outside–in signaling via protein kinases and phosphatases. Pharmacological inhibitor studies suggest that the serine/threonine protein phosphatase 1 (PP1) promotes plat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605409/ https://www.ncbi.nlm.nih.gov/pubmed/37887268 http://dx.doi.org/10.3390/cells12202424 |