Opposing Roles for the α Isoform of the Catalytic Subunit of Protein Phosphatase 1 in Inside–Out and Outside–In Integrin Signaling in Murine Platelets

Platelet activation during hemostasis and thrombosis is facilitated by agonist-induced inside–out and integrin α(IIb)β(3)-initiated outside–in signaling via protein kinases and phosphatases. Pharmacological inhibitor studies suggest that the serine/threonine protein phosphatase 1 (PP1) promotes plat...

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Detalles Bibliográficos
Autores principales: Khatlani, Tanvir, Pradhan, Subhashree, Langlois, Kimberly, Subramanyam, Deepika, Rumbaut, Rolando E., Vijayan, K. Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605409/
https://www.ncbi.nlm.nih.gov/pubmed/37887268
http://dx.doi.org/10.3390/cells12202424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605409/
https://www.ncbi.nlm.nih.gov/pubmed/37887268
http://dx.doi.org/10.3390/cells12202424

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