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NanoFIRE: A NanoLuciferase and Fluorescent Integrated Reporter Element for Robust and Sensitive Investigation of HIF and Other Signalling Pathways

The Hypoxia Inducible Factor (HIF) transcription factors are imperative for cell adaption to low oxygen conditions and development; however, they also contribute to ischaemic disease and cancer. To identify novel genetic regulators which target the HIF pathway or small molecules for therapeutic use,...

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Detalles Bibliográficos
Autores principales: Roennfeldt, Alison E., Allen, Timothy P., Trowbridge, Brooke N., Beard, Michael R., Whitelaw, Murray L., Russell, Darryl L., Bersten, David C., Peet, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605489/
https://www.ncbi.nlm.nih.gov/pubmed/37892227
http://dx.doi.org/10.3390/biom13101545