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GPR4 Knockout Attenuates Intestinal Inflammation and Forestalls the Development of Colitis-Associated Colorectal Cancer in Murine Models

SIMPLE SUMMARY: Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, is a debilitating condition with chronic inflammation in the digestive tract. Patients with IBD are at higher risk of developing colitis-associated colorectal cancer (CAC) compared with the general po...

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Detalles Bibliográficos
Autores principales: Marie, Mona A., Sanderlin, Edward J., Hoffman, Alexander P., Cashwell, Kylie D., Satturwar, Swati, Hong, Heng, Sun, Ying, Yang, Li V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605520/
https://www.ncbi.nlm.nih.gov/pubmed/37894341
http://dx.doi.org/10.3390/cancers15204974