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MicroRNA Expression Patterns Reveal a Role of the TGF-β Family Signaling in AML Chemo-Resistance

SIMPLE SUMMARY: In patients with acute myeloid leukemia (AML), cytarabine-based chemotherapy usually achieves remission, but this is commonly followed by relapse and chemo-resistance. In this study, we aim to establish next-generation sequencing (NGS)-based microRNA expression profiling and pathway...

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Detalles Bibliográficos
Autores principales: Reichelt, Paula, Bernhart, Stephan, Wilke, Franziska, Schwind, Sebastian, Cross, Michael, Platzbecker, Uwe, Behre, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605523/
https://www.ncbi.nlm.nih.gov/pubmed/37894453
http://dx.doi.org/10.3390/cancers15205086