Mutant p53 Gain-of-Function Induces Migration and Invasion through Overexpression of miR-182-5p in Cancer Cells

The master-key TP53 gene is a tumor suppressor that is mutated in more than 50% of human cancers. Some p53 mutants lose their tumor suppressor activity and acquire new oncogenic functions, known as a gain of function (GOF). Recent studies have shown that p53 mutants can exert oncogenic effects throu...

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Detalles Bibliográficos
Autores principales: Madrigal, Tzitzijanik, Ortega-Bernal, Daniel, Herrera, Luis A., González-De la Rosa, Claudia Haydée, Domínguez-Gómez, Guadalupe, Aréchaga-Ocampo, Elena, Díaz-Chávez, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605582/
https://www.ncbi.nlm.nih.gov/pubmed/37887350
http://dx.doi.org/10.3390/cells12202506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605582/
https://www.ncbi.nlm.nih.gov/pubmed/37887350
http://dx.doi.org/10.3390/cells12202506

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