Cargando…

Defucosylated Monoclonal Antibody (H(2)Mab-139-mG(2a)-f) Exerted Antitumor Activities in Mouse Xenograft Models of Breast Cancers against Human Epidermal Growth Factor Receptor 2

The clinically approved human epidermal growth factor receptor 2 (HER2)-targeting monoclonal antibodies (mAbs), trastuzumab, and pertuzumab, target domains IV and II, respectively. Trastuzumab is now the standard treatment for HER2-overexpressed breast and gastric cancers, and trastuzumab in combina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suzuki, Hiroyuki, Ohishi, Tomokazu, Nanamiya, Ren, Kawada, Manabu, Kaneko, Mika K., Kato, Yukinari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605610/ https://www.ncbi.nlm.nih.gov/pubmed/37886932 http://dx.doi.org/10.3390/cimb45100488

Ejemplares similares

A Defucosylated Anti-EpCAM Monoclonal Antibody (EpMab-37-mG(2a)-f) Exerts Antitumor Activity in Xenograft Model
por: Asano, Teizo, et al.
Publicado: (2022)

A defucosylated anti-PD-L1 monoclonal antibody 13-mG(2a)-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
por: Takei, Junko, et al.
Publicado: (2020)

A Humanized and Defucosylated Antibody against Podoplanin (humLpMab-23-f) Exerts Antitumor Activities in Human Lung Cancer and Glioblastoma Xenograft Models
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

H(2)Mab-19, an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts
por: Takei, Junko, et al.
Publicado: (2020)

An anti-TROP2 monoclonal antibody TrMab-6 exerts antitumor activity in breast cancer mouse xenograft models
por: Tanaka, Tomohiro, et al.
Publicado: (2021)

Defucosylated Mouse–Dog Chimeric Anti-EGFR Antibody Exerts Antitumor Activities in Mouse Xenograft Models of Canine Tumors
por: Li, Guanjie, et al.
Publicado: (2021)

Defucosylated mouse-dog chimeric anti-HER2 monoclonal antibody exerts antitumor activities in mouse xenograft models of canine tumors
por: Suzuki, Hiroyuki, et al.
Publicado: (2022)

A defucosylated anti-CD44 monoclonal antibody 5-mG(2a)-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
por: Takei, Junko, et al.
Publicado: (2020)

Antitumor activities of a defucosylated anti-EpCAM monoclonal antibody in colorectal carcinoma xenograft models
por: Li, Guanjie, et al.
Publicado: (2023)

A cancer-specific anti-podocalyxin monoclonal antibody (60-mG(2a)-f) exerts antitumor effects in mouse xenograft models of pancreatic carcinoma
por: Kaneko, Mika K., et al.
Publicado: (2020)

Anti-EGFR monoclonal antibody 134-mG(2a) exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma
por: Hosono, Hideki, et al.
Publicado: (2020)

The anti-epithelial cell adhesion molecule (EpCAM) monoclonal antibody EpMab-16 exerts antitumor activity in a mouse model of colorectal adenocarcinoma
por: Hosono, Hideki, et al.
Publicado: (2020)

The mouse–canine chimeric anti-dog podoplanin antibody P38B exerts antitumor activity in mouse xenograft models
por: Kato, Yukinari, et al.
Publicado: (2018)

Anti-HER3 monoclonal antibody exerts antitumor activity in a mouse model of colorectal adenocarcinoma
por: Asano, Teizo, et al.
Publicado: (2021)

Antitumor Activity of an Anti-EGFR/HER2 Bispecific Antibody in a Mouse Xenograft Model of Canine Osteosarcoma
por: Tateyama, Nami, et al.
Publicado: (2022)

A novel anti-EGFR monoclonal antibody (EMab-17) exerts antitumor activity against oral squamous cell carcinomas via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity
por: Takei, Junko, et al.
Publicado: (2020)

Anti-podocalyxin antibody exerts antitumor effects via antibody-dependent cellular cytotoxicity in mouse xenograft models of oral squamous cell carcinoma
por: Itai, Shunsuke, et al.
Publicado: (2018)

Antibody–Drug Conjugates Using Mouse–Canine Chimeric Anti-Dog Podoplanin Antibody Exerts Antitumor Activity in a Mouse Xenograft Model
por: Kato, Yukinari, et al.
Publicado: (2020)

Anti-EpCAM monoclonal antibody exerts antitumor activity against oral squamous cell carcinomas
por: Kaneko, Mika K., et al.
Publicado: (2020)

Current Targeted Therapy for Metastatic Colorectal Cancer
por: Ohishi, Tomokazu, et al.
Publicado: (2023)

Anti-Metastatic Activity of an Anti-EGFR Monoclonal Antibody against Metastatic Colorectal Cancer with KRAS p.G13D Mutation
por: Ohishi, Tomokazu, et al.
Publicado: (2020)

Development and characterization of TrMab-6, a novel anti-TROP2 monoclonal antibody for antigen detection in breast cancer
por: Sayama, Yusuke, et al.
Publicado: (2021)

Antitumor activity of chLpMab‐2, a human–mouse chimeric cancer‐specific antihuman podoplanin antibody, via antibody‐dependent cellular cytotoxicity
por: Kaneko, Mika K., et al.
Publicado: (2017)

Establishment of a novel anti-TROP2 monoclonal antibody TrMab-29 for immunohistochemical analysis
por: Sayama, Yusuke, et al.
Publicado: (2021)

Podocalyxin is crucial for the growth of oral squamous cell carcinoma cell line HSC-2
por: Itai, Shunsuke, et al.
Publicado: (2018)

Determination of critical epitope of PcMab-47 against human podocalyxin
por: Itai, Shunsuke, et al.
Publicado: (2018)

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans
por: Mizushima, Tsunehiro, et al.
Publicado: (2011)

Epitope mapping of an anti-diacylglycerol kinase delta monoclonal antibody DdMab-1
por: Sano, Masato, et al.
Publicado: (2020)

Famitinib exerted powerful antitumor activity in human gastric cancer cells and xenografts
por: Ge, Sai, et al.
Publicado: (2016)

LpMab-12 Established by CasMab Technology Specifically Detects Sialylated O-Glycan on Thr52 of Platelet Aggregation-Stimulating Domain of Human Podoplanin
por: Kato, Yukinari, et al.
Publicado: (2016)

CD16 pre-ligation by defucosylated tumor-targeting mAb sensitizes human NK cells to γ(c) cytokine stimulation via PI3K/mTOR axis
por: Capuano, Cristina, et al.
Publicado: (2020)

H(2)Mab-77 is a Sensitive and Specific Anti-HER2 Monoclonal Antibody Against Breast Cancer
por: Itai, Shunsuke, et al.
Publicado: (2017)

Characterization of Monoclonal Antibody LpMab-3 Recognizing Sialylated Glycopeptide of Podoplanin
por: Oki, Hiroharu, et al.
Publicado: (2015)

Establishment of C(20)Mab-11, a novel anti-CD20 monoclonal antibody, for the detection of B cells
por: Furusawa, Yoshikazu, et al.
Publicado: (2020)

Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C(9)Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method
por: Kobayashi, Hiyori, et al.
Publicado: (2023)

Establishment and Epitope Mapping of Anti-Diacylglycerol Kinase α Monoclonal Antibody DaMab-8 for Immunohistochemical Analyses
por: Sano, Masato, et al.
Publicado: (2020)

Lycorine exerts antitumor activity against osteosarcoma cells in vitro and in vivo xenograft model through the JAK2/STAT3 pathway
por: Hu, Hongzhi, et al.
Publicado: (2019)

Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1
por: Liu, Xing, et al.
Publicado: (2013)

Detection of high PD-L1 expression in oral cancers by a novel monoclonal antibody L(1)Mab-4
por: Yamada, Shinji, et al.
Publicado: (2018)

RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo
por: Hendruschk, Sandy, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ts4gq0mucen28klvs8auqve0g7