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Proinflammatory IFNγ Is Produced by but Not Required for the Generation of Eomes(+) Thymic Innate CD8 T Cells

Innate CD8 T cells are proinflammatory effector T cells that achieve functional maturation in the thymus prior to their export into and maturation in peripheral tissues. Innate CD8 T cells produce the Th1 cytokine IFNγ but depend on the Th2 cytokine IL-4 for their generation. Thus, innate CD8 T cell...

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Detalles Bibliográficos
Autores principales: Won, Hee Yeun, Liman, Nurcin, Li, Can, Park, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605631/
https://www.ncbi.nlm.nih.gov/pubmed/37887277
http://dx.doi.org/10.3390/cells12202433