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Proinflammatory IFNγ Is Produced by but Not Required for the Generation of Eomes(+) Thymic Innate CD8 T Cells
Innate CD8 T cells are proinflammatory effector T cells that achieve functional maturation in the thymus prior to their export into and maturation in peripheral tissues. Innate CD8 T cells produce the Th1 cytokine IFNγ but depend on the Th2 cytokine IL-4 for their generation. Thus, innate CD8 T cell...
Autores principales: | Won, Hee Yeun, Liman, Nurcin, Li, Can, Park, Jung-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605631/ https://www.ncbi.nlm.nih.gov/pubmed/37887277 http://dx.doi.org/10.3390/cells12202433 |
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