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Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food

Food and waterborne illnesses are still a major concern in health and food safety areas. Every year, almost 0.42 million and 2.2 million deaths related to food and waterborne illness are reported worldwide, respectively. In foodborne pathogens, bacteria such as Salmonella, Shiga-toxin producer Esche...

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Autores principales: Valenzuela-Amaro, Hiram Martin, Aguayo-Acosta, Alberto, Meléndez-Sánchez, Edgar Ricardo, de la Rosa, Orlando, Vázquez-Ortega, Perla Guadalupe, Oyervides-Muñoz, Mariel Araceli, Sosa-Hernández, Juan Eduardo, Parra-Saldívar, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605657/
https://www.ncbi.nlm.nih.gov/pubmed/37887115
http://dx.doi.org/10.3390/bios13100922
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author Valenzuela-Amaro, Hiram Martin
Aguayo-Acosta, Alberto
Meléndez-Sánchez, Edgar Ricardo
de la Rosa, Orlando
Vázquez-Ortega, Perla Guadalupe
Oyervides-Muñoz, Mariel Araceli
Sosa-Hernández, Juan Eduardo
Parra-Saldívar, Roberto
author_facet Valenzuela-Amaro, Hiram Martin
Aguayo-Acosta, Alberto
Meléndez-Sánchez, Edgar Ricardo
de la Rosa, Orlando
Vázquez-Ortega, Perla Guadalupe
Oyervides-Muñoz, Mariel Araceli
Sosa-Hernández, Juan Eduardo
Parra-Saldívar, Roberto
author_sort Valenzuela-Amaro, Hiram Martin
collection PubMed
description Food and waterborne illnesses are still a major concern in health and food safety areas. Every year, almost 0.42 million and 2.2 million deaths related to food and waterborne illness are reported worldwide, respectively. In foodborne pathogens, bacteria such as Salmonella, Shiga-toxin producer Escherichia coli, Campylobacter, and Listeria monocytogenes are considered to be high-concern pathogens. High-concern waterborne pathogens are Vibrio cholerae, leptospirosis, Schistosoma mansoni, and Schistosima japonicum, among others. Despite the major efforts of food and water quality control to monitor the presence of these pathogens of concern in these kinds of sources, foodborne and waterborne illness occurrence is still high globally. For these reasons, the development of novel and faster pathogen-detection methods applicable to real-time surveillance strategies are required. Methods based on biosensor devices have emerged as novel tools for faster detection of food and water pathogens, in contrast to traditional methods that are usually time-consuming and are unsuitable for large-scale monitoring. Biosensor devices can be summarized as devices that use biochemical reactions with a biorecognition section (isolated enzymes, antibodies, tissues, genetic materials, or aptamers) to detect pathogens. In most cases, biosensors are based on the correlation of electrical, thermal, or optical signals in the presence of pathogen biomarkers. The application of nano and molecular technologies allows the identification of pathogens in a faster and high-sensibility manner, at extremely low-pathogen concentrations. In fact, the integration of gold, silver, iron, and magnetic nanoparticles (NP) in biosensors has demonstrated an improvement in their detection functionality. The present review summarizes the principal application of nanomaterials and biosensor-based devices for the detection of pathogens in food and water samples. Additionally, it highlights the improvement of biosensor devices through nanomaterials. Nanomaterials offer unique advantages for pathogen detection. The nanoscale and high specific surface area allows for more effective interaction with pathogenic agents, enhancing the sensitivity and selectivity of the biosensors. Finally, biosensors’ capability to functionalize with specific molecules such as antibodies or nucleic acids facilitates the specific detection of the target pathogens.
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spelling pubmed-106056572023-10-28 Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food Valenzuela-Amaro, Hiram Martin Aguayo-Acosta, Alberto Meléndez-Sánchez, Edgar Ricardo de la Rosa, Orlando Vázquez-Ortega, Perla Guadalupe Oyervides-Muñoz, Mariel Araceli Sosa-Hernández, Juan Eduardo Parra-Saldívar, Roberto Biosensors (Basel) Review Food and waterborne illnesses are still a major concern in health and food safety areas. Every year, almost 0.42 million and 2.2 million deaths related to food and waterborne illness are reported worldwide, respectively. In foodborne pathogens, bacteria such as Salmonella, Shiga-toxin producer Escherichia coli, Campylobacter, and Listeria monocytogenes are considered to be high-concern pathogens. High-concern waterborne pathogens are Vibrio cholerae, leptospirosis, Schistosoma mansoni, and Schistosima japonicum, among others. Despite the major efforts of food and water quality control to monitor the presence of these pathogens of concern in these kinds of sources, foodborne and waterborne illness occurrence is still high globally. For these reasons, the development of novel and faster pathogen-detection methods applicable to real-time surveillance strategies are required. Methods based on biosensor devices have emerged as novel tools for faster detection of food and water pathogens, in contrast to traditional methods that are usually time-consuming and are unsuitable for large-scale monitoring. Biosensor devices can be summarized as devices that use biochemical reactions with a biorecognition section (isolated enzymes, antibodies, tissues, genetic materials, or aptamers) to detect pathogens. In most cases, biosensors are based on the correlation of electrical, thermal, or optical signals in the presence of pathogen biomarkers. The application of nano and molecular technologies allows the identification of pathogens in a faster and high-sensibility manner, at extremely low-pathogen concentrations. In fact, the integration of gold, silver, iron, and magnetic nanoparticles (NP) in biosensors has demonstrated an improvement in their detection functionality. The present review summarizes the principal application of nanomaterials and biosensor-based devices for the detection of pathogens in food and water samples. Additionally, it highlights the improvement of biosensor devices through nanomaterials. Nanomaterials offer unique advantages for pathogen detection. The nanoscale and high specific surface area allows for more effective interaction with pathogenic agents, enhancing the sensitivity and selectivity of the biosensors. Finally, biosensors’ capability to functionalize with specific molecules such as antibodies or nucleic acids facilitates the specific detection of the target pathogens. MDPI 2023-10-11 /pmc/articles/PMC10605657/ /pubmed/37887115 http://dx.doi.org/10.3390/bios13100922 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Valenzuela-Amaro, Hiram Martin
Aguayo-Acosta, Alberto
Meléndez-Sánchez, Edgar Ricardo
de la Rosa, Orlando
Vázquez-Ortega, Perla Guadalupe
Oyervides-Muñoz, Mariel Araceli
Sosa-Hernández, Juan Eduardo
Parra-Saldívar, Roberto
Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food
title Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food
title_full Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food
title_fullStr Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food
title_full_unstemmed Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food
title_short Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food
title_sort emerging applications of nanobiosensors in pathogen detection in water and food
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605657/
https://www.ncbi.nlm.nih.gov/pubmed/37887115
http://dx.doi.org/10.3390/bios13100922
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