R-Loops in Genome Instability and Cancer

SIMPLE SUMMARY: R-loops are three-stranded structures consisting of an RNA–DNA hybrid and an unpaired single-stranded DNA (ssDNA), with biological implications in cellular physiology and pathological conditions. R-loops interfere with DNA repair pathways and activate oncogenes, leading to dysregulat...

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Detalles Bibliográficos
Autores principales: Li, Fang, Zafar, Alyan, Luo, Liang, Denning, Ariana Maria, Gu, Jun, Bennett, Ansley, Yuan, Fenghua, Zhang, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605827/
https://www.ncbi.nlm.nih.gov/pubmed/37894353
http://dx.doi.org/10.3390/cancers15204986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605827/
https://www.ncbi.nlm.nih.gov/pubmed/37894353
http://dx.doi.org/10.3390/cancers15204986

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