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Cucurbitacin E Exerts Anti-Proliferative Activity via Promoting p62-Dependent Apoptosis in Human Non-Small-Cell Lung Cancer A549 Cells

EGFR tyrosine kinase inhibitors (TKIs) are the first-line treatment for advanced EGFR-mutated non-small-cell lung cancer (NSCLC). However, NSCLC patients with wild-type EGFR and KRAS mutation are ineligible for EGFR-TKIs. Therefore, the discovery of new therapeutic agents is urgently needed for NSCL...

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Detalles Bibliográficos
Autores principales: Hsu, Han-Lin, Lin, Bo-Jyun, Lin, Yu-Chen, Tu, Chih-Chieh, Nguyen, Nham-Linh, Wang, Ching-Chiung, Chen, Mei-Chuan, Chen, Chun-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605876/
https://www.ncbi.nlm.nih.gov/pubmed/37886957
http://dx.doi.org/10.3390/cimb45100514