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A Cascade Signal Amplification Strategy for the Ultrasensitive Fluorescence Detection of Cu(2+) via λ-Exonuclease-Assisted Target Recycling with Mismatched Catalytic Hairpin Assembly

Herein, an ultrasensitive DNAzyme-based fluorescence biosensor for detecting Cu(2+) was designed using the cascade signal amplification strategy, coupling λ-exonuclease-assisted target recycling and mismatched catalytic hairpin assembly (MCHA). In the designed detection system, the target, Cu(2+), c...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Liu, Chen, He, Liqiong, Liu, Jinquan, Li, Le, Yang, Shengyuan, Tan, Yan, Liu, Xing, Xiao, Xilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605925/
https://www.ncbi.nlm.nih.gov/pubmed/37887111
http://dx.doi.org/10.3390/bios13100918