A CRISPR Screen Identifies the E3 Ubiquitin Ligase Rfwd2 as a Negative Regulator of Glucose Uptake in Brown Adipocytes

Brown adipose tissue activation increases energy expenditure and has been shown to improve glucose tolerance, making it a promising target for the treatment of obesity and type 2 diabetes. Brown adipocytes differentiate into cells with multilocular lipid droplets, which can efficiently absorb and ox...

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Detalles Bibliográficos
Autores principales: Lynes, Matthew D., Huang, Qian, Cora, Carolina, Su, Sheng-Chiang, Yi, Peng, Tseng, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606202/
https://www.ncbi.nlm.nih.gov/pubmed/37895214
http://dx.doi.org/10.3390/genes14101865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606202/
https://www.ncbi.nlm.nih.gov/pubmed/37895214
http://dx.doi.org/10.3390/genes14101865

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