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Dupuytren’s Disease Is Mediated by Insufficient TGF-β1 Release and Degradation

Dupuytren’s disease (DD) is a fibroproliferative disorder affecting the palmar fascia, causing functional restrictions of the hand and thereby limiting patients’ daily lives. The disturbed and excessive myofibroblastogenesis, causing DD, is mainly induced by transforming growth factor (TGF)-β1. But,...

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Detalles Bibliográficos
Autores principales: Oezel, Lisa, Wohltmann, Marie, Gondorf, Nele, Wille, Julia, Güven, Irmak, Windolf, Joachim, Thelen, Simon, Jaekel, Carina, Grotheer, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606262/
https://www.ncbi.nlm.nih.gov/pubmed/37894778
http://dx.doi.org/10.3390/ijms242015097