Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes

Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic str...

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Detalles Bibliográficos
Autores principales: Nejat, Shadi, Menikdiwela, Kalhara R., Efotte, Aliyah, Scoggin, Shane, Vandanmagsar, Bolormaa, Thornalley, Paul J., Dehbi, Mohammed, Moustaid-Moussa, Naima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606339/
https://www.ncbi.nlm.nih.gov/pubmed/37895206
http://dx.doi.org/10.3390/genes14101857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606339/
https://www.ncbi.nlm.nih.gov/pubmed/37895206
http://dx.doi.org/10.3390/genes14101857

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