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Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4

TCR-like chimeric antigen receptor (CAR-T) cell therapy has emerged as a game-changing strategy in cancer immunotherapy, offering a broad spectrum of potential antigen targets, particularly in solid tumors containing intracellular antigens. In this study, we investigated the cytotoxicity and functio...

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Detalles Bibliográficos
Autores principales: Alsalloum, Alaa, Shevchenko, Julia, Fisher, Marina, Philippova, Julia, Perik-Zavodskii, Roman, Perik-Zavodskaia, Olga, Alrhmoun, Saleh, Lopatnikova, Julia, Vasily, Kurilin, Volynets, Marina, Zavjalov, Evgenii, Solovjeva, Olga, Akahori, Yasushi, Shiku, Hiroshi, Silkov, Alexander, Sennikov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606439/
https://www.ncbi.nlm.nih.gov/pubmed/37894816
http://dx.doi.org/10.3390/ijms242015134