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Notch Signaling Regulates Mouse Perivascular Adipose Tissue Function via Mitochondrial Pathways

Perivascular adipose tissue (PVAT) regulates vascular function by secreting vasoactive substances. In mice, Notch signaling is activated in the PVAT during diet-induced obesity, and leads to the loss of the thermogenic phenotype and adipocyte whitening due to increased lipid accumulation. We used th...

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Detalles Bibliográficos
Autores principales: Yang, Chenhao, Yang, Xuehui, Harrington, Anne, Potts, Christian, Kaija, Abigail, Ryzhova, Larisa, Liaw, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606454/
https://www.ncbi.nlm.nih.gov/pubmed/37895313
http://dx.doi.org/10.3390/genes14101964