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Notch Signaling Regulates Mouse Perivascular Adipose Tissue Function via Mitochondrial Pathways
Perivascular adipose tissue (PVAT) regulates vascular function by secreting vasoactive substances. In mice, Notch signaling is activated in the PVAT during diet-induced obesity, and leads to the loss of the thermogenic phenotype and adipocyte whitening due to increased lipid accumulation. We used th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606454/ https://www.ncbi.nlm.nih.gov/pubmed/37895313 http://dx.doi.org/10.3390/genes14101964 |