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Identification of Intron Retention in the Slc16a3 Gene Transcript Encoding the Transporter MCT4 in the Brain of Aged and Alzheimer-Disease Model (APPswePS1dE9) Mice

The monocarboxylate transporter 4 (MCT4; Slc16a3) is expressed in the central nervous system, notably by astrocytes. It is implicated in lactate release and the regulation of glycolytic flux. Whether its expression varies during normal and/or pathological aging is unclear. As the presence of its mat...

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Detalles Bibliográficos
Autores principales: EL-Seedy, Ayman, Pellerin, Luc, Page, Guylène, Ladeveze, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606527/
https://www.ncbi.nlm.nih.gov/pubmed/37895298
http://dx.doi.org/10.3390/genes14101949