Activation of Chaperone-Mediated Autophagy Inhibits the Aryl Hydrocarbon Receptor Function by Degrading This Receptor in Human Lung Epithelial Carcinoma A549 Cells

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor and a substrate protein of a Cullin 4B E3 ligase complex responsible for diverse cellular processes. In the lung, this receptor is responsible for the bioactivation of benzo[a]pyrene during tumorigenesis. Realizing that t...

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Detalles Bibliográficos
Autores principales: Xiong, Rui, Shao, Dan, Do, Sandra, Chan, William K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606571/
https://www.ncbi.nlm.nih.gov/pubmed/37894798
http://dx.doi.org/10.3390/ijms242015116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606571/
https://www.ncbi.nlm.nih.gov/pubmed/37894798
http://dx.doi.org/10.3390/ijms242015116

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