The Intrinsically Disordered N Terminus in Atg12 from Yeast Is Necessary for the Functional Structure of the Protein

The Atg12 protein in yeast is an indispensable polypeptide in the highly conserved ubiquitin-like conjugation system operating in the macroautophagy/autophagy pathway. Atg12 is covalently conjugated to Atg5 through the action of Atg7 and Atg10; the Atg12–Atg5 conjugate binds Atg16 to form an E3 liga...

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Detalles Bibliográficos
Autores principales: Popelka, Hana, Lahiri, Vikramjit, Hawkins, Wayne D., da Veiga Leprevost, Felipe, Nesvizhskii, Alexey I., Klionsky, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606595/
https://www.ncbi.nlm.nih.gov/pubmed/37894717
http://dx.doi.org/10.3390/ijms242015036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606595/
https://www.ncbi.nlm.nih.gov/pubmed/37894717
http://dx.doi.org/10.3390/ijms242015036

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