The Expression and Activation of the NF-κB Pathway Correlate with Methotrexate Resistance and Cell Proliferation in Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Although its prognosis continually improves with time, a significant proportion of patients still relapse from the disease because of the leukemia’s resistance to therapy. Methotrexate (MTX), a folic-acid antagonist, is a chemot...

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Detalles Bibliográficos
Autores principales: Canevarolo, Rafael Renatino, Cury, Nathalia Moreno, Yunes, José Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606671/
https://www.ncbi.nlm.nih.gov/pubmed/37895229
http://dx.doi.org/10.3390/genes14101880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606671/
https://www.ncbi.nlm.nih.gov/pubmed/37895229
http://dx.doi.org/10.3390/genes14101880

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