Novel Treatments for PXE: Targeting the Systemic and Local Drivers of Ectopic Calcification

Pseudoxanthoma elasticum (PXE) is a heritable multisystem ectopic calcification disorder. The gene responsible for PXE, ABCC6, encodes ABCC6, a hepatic efflux transporter regulating extracellular inorganic pyrophosphate (PPi), a potent endogenous calcification inhibitor. Recent studies demonstrated...

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Detalles Bibliográficos
Autores principales: Jacobs, Ida Joely, Li, Qiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606721/
https://www.ncbi.nlm.nih.gov/pubmed/37894722
http://dx.doi.org/10.3390/ijms242015041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606721/
https://www.ncbi.nlm.nih.gov/pubmed/37894722
http://dx.doi.org/10.3390/ijms242015041

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