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Novel Treatments for PXE: Targeting the Systemic and Local Drivers of Ectopic Calcification
Pseudoxanthoma elasticum (PXE) is a heritable multisystem ectopic calcification disorder. The gene responsible for PXE, ABCC6, encodes ABCC6, a hepatic efflux transporter regulating extracellular inorganic pyrophosphate (PPi), a potent endogenous calcification inhibitor. Recent studies demonstrated...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606721/ https://www.ncbi.nlm.nih.gov/pubmed/37894722 http://dx.doi.org/10.3390/ijms242015041 |