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Notopterol Suppresses IL-17-Induced Proliferation and Invasion of A549 Lung Adenocarcinoma Cells via Modulation of STAT3, NF-κB, and AP-1 Activation

Interleukine-17 is a proinflammatory cytokine that promotes lung cancer growth and progression though the activation of the STAT3, NF-κB, and AP-1 signaling pathways. Therefore, blocking the IL-17-induced oncogenic pathway is a new strategy for the treatment of lung cancer. Notopterol, a furanocouma...

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Detalles Bibliográficos
Autores principales: Inthanon, Sirinada, Dejkriengkraikul, Pornngarm, Yodkeeree, Supachai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606807/
https://www.ncbi.nlm.nih.gov/pubmed/37894738
http://dx.doi.org/10.3390/ijms242015057