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Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways

Obesity and metabolic syndrome involve chronic low-grade inflammation called metabolic inflammation as well as metabolic derangements from increased endotoxin and free fatty acids. It is debated whether the endoplasmic reticulum (ER) stress in monocytic cells can contribute to amplify metabolic infl...

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Detalles Bibliográficos
Autores principales: Akhter, Nadeem, Wilson, Ajit, Arefanian, Hossein, Thomas, Reeby, Kochumon, Shihab, Al-Rashed, Fatema, Abu-Farha, Mohamed, Al-Madhoun, Ashraf, Al-Mulla, Fahd, Ahmad, Rasheed, Sindhu, Sardar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606873/
https://www.ncbi.nlm.nih.gov/pubmed/37894865
http://dx.doi.org/10.3390/ijms242015186