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Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways
Obesity and metabolic syndrome involve chronic low-grade inflammation called metabolic inflammation as well as metabolic derangements from increased endotoxin and free fatty acids. It is debated whether the endoplasmic reticulum (ER) stress in monocytic cells can contribute to amplify metabolic infl...
Autores principales: | Akhter, Nadeem, Wilson, Ajit, Arefanian, Hossein, Thomas, Reeby, Kochumon, Shihab, Al-Rashed, Fatema, Abu-Farha, Mohamed, Al-Madhoun, Ashraf, Al-Mulla, Fahd, Ahmad, Rasheed, Sindhu, Sardar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606873/ https://www.ncbi.nlm.nih.gov/pubmed/37894865 http://dx.doi.org/10.3390/ijms242015186 |
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