Side-Chain Immune Oxysterols Induce Neuroinflammation by Activating Microglia

In individuals with Alzheimer’s disease, the brain exhibits elevated levels of IL-1β and oxygenated cholesterol molecules (oxysterols). This study aimed to investigate the effects of side-chain oxysterols on IL-1β expression using HMC3 microglial cells and ApoE-deficient mice. Treatment of HMC3 cell...

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Detalles Bibliográficos
Autores principales: Son, Yonghae, Yeo, In-Jun, Hong, Jin-Tae, Eo, Seong-Kug, Lee, Dongjun, Kim, Koanhoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607006/
https://www.ncbi.nlm.nih.gov/pubmed/37894967
http://dx.doi.org/10.3390/ijms242015288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607006/
https://www.ncbi.nlm.nih.gov/pubmed/37894967
http://dx.doi.org/10.3390/ijms242015288

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