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Engineering and Expression Strategies for Optimization of L-Asparaginase Development and Production

Genetic engineering for heterologous expression has advanced in recent years. Model systems such as Escherichia coli, Bacillus subtilis and Pichia pastoris are often used as host microorganisms for the enzymatic production of L-asparaginase, an enzyme widely used in the clinic for the treatment of l...

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Detalles Bibliográficos
Autores principales: Shishparenok, Anastasiya N., Gladilina, Yulia A., Zhdanov, Dmitry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607044/
https://www.ncbi.nlm.nih.gov/pubmed/37894901
http://dx.doi.org/10.3390/ijms242015220