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Normothermic Ex Situ Machine Perfusion of Vascularized Composite Allografts with Oxygen Microcarriers for 12 Hours Using Real-Time Mitochondrial Redox Quantification

Background: Normothermic ex situ perfusion of vascularized composite allografts (VCAs) necessitates high oxygen demand and, thus, increased metabolic activity, which, in turn, requires the use of blood-based perfusion solutions. However, blood-derived perfusates, in turn, constitute an antigenic loa...

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Detalles Bibliográficos
Autores principales: Haug, Valentin, Peng, Yifeng, Tchiloemba, Bianief, Wang, Alice T., Buerger, Florian, Romfh, Padraic, Kneser, Ulrich, Polizzotti, Brian D., Pomahac, Bohdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607057/
https://www.ncbi.nlm.nih.gov/pubmed/37892706
http://dx.doi.org/10.3390/jcm12206568