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Small Molecule Pytren-4QMn Metal Complex Slows down Huntington’s Disease Progression in Male zQ175 Transgenic Mice

Huntington’s disease (HD) is an inherited neurodegenerative disorder considered a rare disease with a prevalence of 5.7 per 100,000 people. It is caused by an autosomal dominant mutation consisting of expansions of trinucleotide repeats that translate into poly-glutamine enlarged mutant huntingtin p...

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Detalles Bibliográficos
Autores principales: Merino, Marián, González, Sonia, Tronch, Mª Carmen, Sánchez-Sánchez, Ana Virginia, Clares, Mª Paz, García-España, Antonio, García-España, Enrique, Mullor, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607077/
https://www.ncbi.nlm.nih.gov/pubmed/37894844
http://dx.doi.org/10.3390/ijms242015153