Double Heterozygosity for Rare Deleterious Variants in the BRCA1 and BRCA2 Genes in a Hungarian Patient with Breast Cancer

Hereditary breast cancer is most commonly attributed to germline BRCA1 and BRCA2 gene variants. The vast majority of BRCA1 and BRCA2 mutation carriers are single heterozygotes, and double heterozygosity (DH) is a very rare finding. Here, we describe the case of a BRCA1/BRCA2 double heterozygous fema...

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Detalles Bibliográficos
Autores principales: Madar, László, Majoros, Viktória, Szűcs, Zsuzsanna, Nagy, Orsolya, Babicz, Tamás, Butz, Henriett, Patócs, Attila, Balogh, István, Koczok, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607119/
https://www.ncbi.nlm.nih.gov/pubmed/37895014
http://dx.doi.org/10.3390/ijms242015334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607119/
https://www.ncbi.nlm.nih.gov/pubmed/37895014
http://dx.doi.org/10.3390/ijms242015334

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