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Preparation of N(In)-Methyl-6-[(18)F]fluoro- and 5-Hydroxy-7-[(18)F]fluorotryptophans as Candidate PET-Tracers for Pathway-Specific Visualization of Tryptophan Metabolism

Tryptophan (Trp) is an essential proteinogenic amino acid and metabolic precursor for several signaling molecules that has been implicated in many physiological and pathological processes. Since the two main branches of Trp metabolism—serotonin biosynthesis and kynurenine pathway—are differently aff...

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Detalles Bibliográficos
Autores principales: Kolks, Niklas, Neumaier, Felix, Neumaier, Bernd, Zlatopolskiy, Boris D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607147/
https://www.ncbi.nlm.nih.gov/pubmed/37894930
http://dx.doi.org/10.3390/ijms242015251