Statins and Cardiomyocyte Metabolism, Friend or Foe?

Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, and are the cornerstone of lipid-lowering treatment. They significantly reduce cardiovascular morbidity and mortality. However, musculoskeletal symptoms are observed in 7 to 29 percent of all users. The mechanism u...

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Detalles Bibliográficos
Autores principales: Somers, Tim, Siddiqi, Sailay, Morshuis, Wim J., Russel, Frans G. M., Schirris, Tom J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607220/
https://www.ncbi.nlm.nih.gov/pubmed/37887864
http://dx.doi.org/10.3390/jcdd10100417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607220/
https://www.ncbi.nlm.nih.gov/pubmed/37887864
http://dx.doi.org/10.3390/jcdd10100417

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