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Impact of Sex and Genetic Variation in Relevant Pharmacogenes on the Pharmacokinetics and Safety of Valsartan, Olmesartan and Hydrochlorothiazide

Drug combination therapy is the most common pharmacological strategy for hypertension management. No pharmacogenetic biomarkers for guiding hypertension pharmacotherapy are available to date. The study population were 64 volunteers from seven bioequivalence trials investigating formulations with val...

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Detalles Bibliográficos
Autores principales: Soria-Chacartegui, Paula, Zubiaur, Pablo, Ochoa, Dolores, Navares-Gómez, Marcos, Abbes, Houwaida, Villapalos-García, Gonzalo, de Miguel, Alejandro, González-Iglesias, Eva, Rodríguez-Lopez, Andrea, Mejía-Abril, Gina, Martín-Vilchez, Samuel, Luquero-Bueno, Sergio, Román, Manuel, Abad-Santos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607223/
https://www.ncbi.nlm.nih.gov/pubmed/37894954
http://dx.doi.org/10.3390/ijms242015265