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Vaping-Induced Proteolysis Causes Airway Surface Dehydration

Proteases such as neutrophil elastase cleave and activate the epithelial sodium channel (ENaC), causing airway dehydration. Our current study explores the impact of increased protease levels in vapers’ airways on ENaC activity and airway dehydration. Human bronchial epithelial cultures (HBECs) were...

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Detalles Bibliográficos
Autores principales: Ghosh, Arunava, Coakley, Raymond D., Alexis, Neil E., Tarran, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607227/
https://www.ncbi.nlm.nih.gov/pubmed/37895029
http://dx.doi.org/10.3390/ijms242015348