Calcium Signaling Consequences of RyR2-S4938F Mutation Expressed in Human iPSC-Derived Cardiomyocytes

Type-2 ryanodine receptor (RyR2) is the major Ca(2+) release channel of the cardiac sarcoplasmic reticulum (SR) that controls the rhythm and strength of the heartbeat, but its malfunction may generate severe arrhythmia leading to sudden cardiac death or heart failure. S4938F-RyR2 mutation in the car...

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Detalles Bibliográficos
Autores principales: Toth, Noemi, Zhang, Xiao-Hua, Zamaro, Alexandra, Morad, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607246/
https://www.ncbi.nlm.nih.gov/pubmed/37894987
http://dx.doi.org/10.3390/ijms242015307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607246/
https://www.ncbi.nlm.nih.gov/pubmed/37894987
http://dx.doi.org/10.3390/ijms242015307

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