Combination of On-Line and Off-Line Two-Dimensional Liquid Chromatography-Mass Spectrometry for Comprehensive Characterization of mAb Charge Variants and Precise Instructions for Rapid Process Development

Charge variants, as an important quality attribute of mAbs, must be comprehensively characterized and monitored during development. However, due to their complex structure, the characterization of charge variants is challenging, labor-intensive, and time-consuming when using traditional approaches....

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Detalles Bibliográficos
Autores principales: Jin, Xiaoqing, He, Bingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607358/
https://www.ncbi.nlm.nih.gov/pubmed/37894864
http://dx.doi.org/10.3390/ijms242015184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607358/
https://www.ncbi.nlm.nih.gov/pubmed/37894864
http://dx.doi.org/10.3390/ijms242015184

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