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Hematologic Neoplasms Associated with Down Syndrome: Cellular and Molecular Heterogeneity of the Diseases

The molecular basis of Down syndrome (DS) predisposition to leukemia is not fully understood but involves various factors such as chromosomal abnormalities, oncogenic mutations, epigenetic alterations, and changes in selection dynamics. Myeloid leukemia associated with DS (ML-DS) is preceded by a pr...

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Detalles Bibliográficos
Autores principales: Peroni, Edoardo, Gottardi, Michele, D’Antona, Lucia, Randi, Maria Luigia, Rosato, Antonio, Coltro, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607483/
https://www.ncbi.nlm.nih.gov/pubmed/37895004
http://dx.doi.org/10.3390/ijms242015325