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Short-Term Inhibition of Translation by Cycloheximide Concurrently Affects Mitochondrial Function and Insulin Secretion in Islets from Female Mice

Since glucose stimulates protein biosynthesis in beta cells concomitantly with the stimulation of insulin release, the possible interaction of both processes was explored. The protein biosynthesis was inhibited by 10 μM cycloheximide (CHX) 60 min prior to the stimulation of perifused, freshly isolat...

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Detalles Bibliográficos
Autores principales: Alshafei, Mohammed, Schulze, Torben, Morsi, Mai, Panten, Uwe, Rustenbeck, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607510/
https://www.ncbi.nlm.nih.gov/pubmed/37895141
http://dx.doi.org/10.3390/ijms242015464