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Short-Term Inhibition of Translation by Cycloheximide Concurrently Affects Mitochondrial Function and Insulin Secretion in Islets from Female Mice
Since glucose stimulates protein biosynthesis in beta cells concomitantly with the stimulation of insulin release, the possible interaction of both processes was explored. The protein biosynthesis was inhibited by 10 μM cycloheximide (CHX) 60 min prior to the stimulation of perifused, freshly isolat...
Autores principales: | Alshafei, Mohammed, Schulze, Torben, Morsi, Mai, Panten, Uwe, Rustenbeck, Ingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607510/ https://www.ncbi.nlm.nih.gov/pubmed/37895141 http://dx.doi.org/10.3390/ijms242015464 |
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