In Vitro Experiments on the Effects of GP-2250 on BRAF-Mutated Melanoma Cell Lines and Benign Melanocytes

Enhanced glycolysis (Warburg effect) driven by the BRAF oncogene, dysregulated GAPDH expression, and activation of the PI3K/AKT/mTOR signaling pathway may significantly contribute to the resistance-targeted therapy of BRAF-mutated melanomas. Therefore, we aimed to study for the first time the anti-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gambichler, Thilo, Harnischfeger, Friederike, Skrygan, Marina, Majchrzak-Stiller, Britta, Buchholz, Marie, Müller, Thomas, Braumann, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607550/
https://www.ncbi.nlm.nih.gov/pubmed/37895015
http://dx.doi.org/10.3390/ijms242015336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607550/
https://www.ncbi.nlm.nih.gov/pubmed/37895015
http://dx.doi.org/10.3390/ijms242015336

Ejemplares similares