Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53

The Hippo pathway mediates renal maladaptive repair after acute kidney injury (AKI), which has been considered a driving force in the progression to chronic kidney disease (CKD). LATS2, a core kinase of the Hippo pathway, exerts non-Hippo-dependent functions in the regulation of the cell cycle and c...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Chi, Zheng, Zhihuang, Xu, Kexin, Cheng, Guozhe, Wu, Huijuan, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607662/
https://www.ncbi.nlm.nih.gov/pubmed/37894939
http://dx.doi.org/10.3390/ijms242015258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607662/
https://www.ncbi.nlm.nih.gov/pubmed/37894939
http://dx.doi.org/10.3390/ijms242015258

Ejemplares similares