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Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53

The Hippo pathway mediates renal maladaptive repair after acute kidney injury (AKI), which has been considered a driving force in the progression to chronic kidney disease (CKD). LATS2, a core kinase of the Hippo pathway, exerts non-Hippo-dependent functions in the regulation of the cell cycle and c...

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Detalles Bibliográficos
Autores principales:	Zhang, Chi, Zheng, Zhihuang, Xu, Kexin, Cheng, Guozhe, Wu, Huijuan, Liu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607662/ https://www.ncbi.nlm.nih.gov/pubmed/37894939 http://dx.doi.org/10.3390/ijms242015258

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