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The Significance of Microenvironmental and Circulating Lactate in Breast Cancer

Lactate represents the main product of pyruvate reduction catalyzed by the lactic dehydrogenase family of enzymes. Cancer cells utilize great quantities of glucose, shifting toward a glycolytic metabolism. With the contribution of tumor stromal cells and under hypoxic conditions, this leads toward t...

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Detalles Bibliográficos
Autores principales: Frisardi, Vincenza, Canovi, Simone, Vaccaro, Salvatore, Frazzi, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607673/
https://www.ncbi.nlm.nih.gov/pubmed/37895048
http://dx.doi.org/10.3390/ijms242015369