The Effect of Dexmedetomidine on the Mini-Cog Score and High-Mobility Group Box 1 Levels in Elderly Patients with Postoperative Neurocognitive Disorders Undergoing Orthopedic Surgery

Dexmedetomidine prevents postoperative cognitive dysfunction by inhibiting high-mobility group box 1 (HMGB1), which acts as an inflammatory marker. This study investigated the HMGB1 levels and the cognitive function using a Mini-Cog© score in elderly patients undergoing orthopedic surgery with dexme...

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Detalles Bibliográficos
Autores principales: Yoo, Seung Hee, Jue, Mi Jin, Kim, Yu-Hee, Cho, Sooyoung, Kim, Won-joong, Kim, Kye-Min, Han, Jong In, Lee, Heeseung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607676/
https://www.ncbi.nlm.nih.gov/pubmed/37892748
http://dx.doi.org/10.3390/jcm12206610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607676/
https://www.ncbi.nlm.nih.gov/pubmed/37892748
http://dx.doi.org/10.3390/jcm12206610

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