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Dissecting the Impact of Vascular Smooth Muscle Cell ABCA1 versus ABCG1 Expression on Cholesterol Efflux and Macrophage-like Cell Transdifferentiation: The Role of SR-BI

Cholesterol-laden macrophages are recognized as a major contributor to atherosclerosis. However, recent evidence indicates that vascular smooth muscle cells (VSMC) that accumulate cholesterol and transdifferentiate into a macrophage-like cell (MLC) phenotype also play a role in atherosclerosis. Ther...

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Detalles Bibliográficos
Autores principales: Oladosu, Olanrewaju, Esobi, Ikechukwu C., Powell, Rhonda R., Bruce, Terri, Stamatikos, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607678/
https://www.ncbi.nlm.nih.gov/pubmed/37887863
http://dx.doi.org/10.3390/jcdd10100416