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Cardiovascular Risk Associated with Alpha-1 Antitrypsin Deficiency (AATD) Genotypes: A Meta-Analysis with Meta-Regressions

Background. Alpha-1 antitrypsin deficiency (AATD) can result in severe liver and respiratory disorders. The uninhibited elastase activity on the elastic tissue of arterial walls suggests that AATD may also impact vascular health. Thus, we performed a meta-analysis of the studies evaluating cardiovas...

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Detalles Bibliográficos
Autores principales: Ambrosino, Pasquale, Marcuccio, Giuseppina, Lombardi, Carmen, D’Anna, Silvestro Ennio, Sanduzzi Zamparelli, Stefano, Mancusi, Costantino, Spedicato, Giorgio Alfredo, Motta, Andrea, Maniscalco, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607733/
https://www.ncbi.nlm.nih.gov/pubmed/37892629
http://dx.doi.org/10.3390/jcm12206490